Article pdf available december 1998 with 850 reads. Multiple imputation is a widely used method for handling missing data, but its use for composite outcomes has been seldom discussed. Multiple imputation and its application is aimed at quantitative researchers and students in the medical and social sciences with the aim of clarifying the issues raised by the analysis of incomplete data data, outlining the rationale for mi and describing how to consider and address the issues that arise in its application. Multiple imputation was designed to handle the problem of missing data in publicuse data bases where the database constructor and the. Multiple imputation of missing composite outcomes in. In the 2017 nsch, missing values were imputed for several demographic variables used in the construction of survey weights. These multiple complete datasets are then analysed in parallel. What i really want is the pooled imputation as used in the regression i.
The idea of multiple imputation for missing data was first proposed by rubin 1977. Two algorithms for producing multiple imputations for missing data are evaluated with simulated data. Multiple imputation and its application is aimed at quantitative researchers and students in the medical and social sciences with the aim of clarifying the issues raised by the analysis of incomplete data data, outlining the rationale for mi and describing how to consider and. Multiple imputation of missing income data in the national health. Multiple imputation for continuous and categorical data. When and how should multiple imputation be used for. Multiple imputation was designed to handle the problem of missing data in publicuse databases where the database constructor and the ultimate user are distinct entities. The objective is valid frequency inference for ultimate users who in general have access only to completedata software and possess limited knowledge of specific reasons and. I suppose that you know that increasing the sample size in this way does not help you to get more precise estimates. We use m to refer to the number of imputations and mto refer to each individual imputation. For more information on dark deposits, see our faq. Abstract multiple imputation was designed to handle the problem of missing data in publicuse data bases where the database constructor and the ultimate user. We are interested in the mean difference in outcome between two treatment groups, denoted by q. Journal of the american statistical association, 91, 473489.
Some methods use double loops methods that actually combine multiple imputation and. Ive never done imputation myself in one scenario another analyst did it in sas, and in another case imputation was spatial mitools is nice for this scenario thomas lumley, author of mitools and survey. Two algorithms for producing multiple imputations for missing data are. Missing data takes many forms and can be attributed to many causes. The objective is valid frequency inference for ultimate users who in general have access. A statistical programming story chris smith, cytel inc. Multiple imputation has been used for several years with cross sectional models to deal with missing data. Census bureau multiple imputation details and purpose in the nsch, missing values are imputed for several demographic variables used in the construction of survey weights.
Hence, analysts planning on bayesian inference after multiple imputation should generate a large number of completed datasets. Maybe ive misunderstood what data the regression uses and maybe completeimp, long is what i want to plot. Pdf bayesian imputation methods for missing data researchgate. In recent years, multiple imputation has emerged as a convenient and flexible paradigm for analysing data with missing values. Software using a propensity score classifier with the approximate bayesian bootstrap produces b. Multiple imputation is a simulationbased statistical technique for handling missing data.
Abstract multiple imputation was designed to handle the problem of missing data in publicuse data bases where the database constructor and the ultimate user are distinct entities. Journal of the american statistical association 91. Analyzing data in a multiple imputation framework the nsch public use fpl implicate file contains the imputed values stored in different variables, one for each of the imputed responses. Multiple imputation mi is a popular method to address missing data. Multiple imputation mi is an approach for handling missing values in a dataset that allows researchers to use. Its flexibility makes it an adequate tool for times series data as well. Multiple imputation for missing data statistics solutions.
Table 2 shows how the dataset needs to be reorganized to do analyses using the multiple imputation. Missing data analysis using multiple imputation circulation. However, instead of filling in a single value, the distribution of the observed data is used to estimate multiple values that reflect the uncertainty around the true value. The objective is valid frequency inference for ultimate users who in general have access only to completedata software and possess limited knowledge of specific reasons and models for nonresponse. Multiple imputation southern research station usda. Multipleimputation analysis using statas mi command. Multiple imputation of family income and personal earnings in. A comparison of inclusive and restrictive strategies in modern missing data procedures.
Combining multiple imputation and bootstrap in the analysis. Pdf temporal changes in methods for collecting longitudinal data can generate inconsistent distributions of affected variables, but effects on. Multiple imputation for missing data via sequential. Multiple imputation originated in the early 1970s, and has gained increasing popularity over the years. Multiple imputation was designed to handle the problem of missing data in public use data bases where the database constructor and the. Although it is known that the outcome should be included in the imputation model when imputing missing covariate values, it is not known whether it should be imputed. Comparing joint and conditional approaches jonathan kropko. With a slight abuse of the terminology, we will use the term imputation to mean the data where missing values are replaced with one set of plausible values. The following is the procedure for conducting the multiple imputation for missing data that was created by rubin in 1987. Whilst standard multiple imputation methodology can be used directly for the composite outcome, the distribution of a composite outcome may be of a complicated form and perhaps not amenable to statistical modelling.
Journal of the american statistical association 91434. Pdf i analyze a series of techniques designed for replacing missing data. Child sex, race, and hispanic origin were imputed using hotdeck imputation while adult 1 education and household size were imputed using sequential regression imputation methods. Multiple imputation mi is a simulationbased approach for analyzing incomplete data.
These variables contain both fully reported and imputed values. An imputation model for dropouts in unemployment data in. When and how should multiple imputation be used for handling. For each of the 20 imputed data sets, a different value has been imputed for bmi. Pdf using multiple imputation to address missing values. According to complete combined administrative data, the employment rate among dropouts was close to 50 for the years 1992 to 2006, but from 2007 the employment rate has dropped to 40 or less. Child sex, race, and hispanic origin are imputed using hotdeck imputation while adult 1. Multiple imputation for missing data is an attractive method for handling missing data in multivariate analysis. Multiple imputation is essentially an iterative form of stochastic imputation. Rubin multiple imputation was designed to handle the problem of missing data in publicuse data bases where the database constructor and the ultimate user are distinct entities. This series is intended to be a practical guide to the technique and its implementation in stata, based on the questions sscc members are asking the ssccs statistical. Bootstrap inference when using multiple imputation arxiv.
Early studies usually relied on comparing these methods with the analysis of complete cases and single substitution based on data with real missing data. Mi replaces missing values with multiple sets of simulated values to complete the data, applies standard analyses to each completed dataset, and adjusts the obtained parameter estimates for missingdata uncertainty rubin 1987, 76. Journal of the american statistical association 91 434. Combining multiple imputation and bootstrap in the. Multiple imputation mi rubin, 1987 is a simple but powerful method for dealing with. To carry out multiple imputation, the team fills in the missing values with draws from some predictive model m times, resulting in m completed data sets. A note on bayesian inference after multiple imputation. Both uncertainty due to prediction errors of the imputed values and uncertainty about the imputation model parameters are reflected using chained equations mice, 18 with predictive mean matching for robustness against nonnormality.
Multiple imputation using chained equations for missing data in. Multiple imputation is frequently used to deal with missing data in healthcare research. Two algorithms for producing multiple imputations for missing data. Multiple imputation approaches for the analysis of. Multiple imputation is appealing because it allows a team of researchers to address the missing data, after which any number of analyses may be performed by standard completedata techniques. Multiple imputation with the multivariate normal model mvn 2 multiple imputation by chained equations mice. These values are then used in the analysis of interest, such as in a ols model, and the.
In the last 20 years or so, sophisticated techniques for dealing with missing data, such as multiple imputation, have been developed 2 and explored in practical research e. Multiple imputation provides a useful strategy for dealing with data sets with missing values. This leads to an ambiguity regarding destination states employment, unemployment, retired, etc. In this example, you will see how to implement a simple form of multiple imputation for time series to fit a garch1,1 model when some of the data are missing. Allison university of pennsylvania address correspondence to paul d. Multiple imputation mi is an approach for handling missing values in a dataset that allows researchers. Multiple imputation of family income and personal earnings. Multiple imputation mi overcomes objections to single imputation by making repeated draws from a model of the distribution of variables that have missing observations, to create a number of complete datasets. Table 1 lists the 10 candidate methods to estimate q and its 95% confidence interval. Pdf using multiple imputation to address missing values of. Mi is becoming an increasingly popular method for sensitivity analyses in order to assess the impact of missing data.
Principled methods of accounting for missing data include full information maximum likelihood estimation, 1, 17, 18 multiple imputation mi 1, 19, 20 and weighting adjustment methods. In this case we have eqjx1 y q1 and euix,y varqix,y, 1. The frequentist multiple imputation approach which fixes the parameters for the imputation model at the maximum likelihood estimates and construct the variance of parameter estimates for the analysis model using the results of robins and wang, 2000, biometrika 87, 1124 is shown to be more efficient. Pdf multiple imputation as a solution to the missing data problem. Introduction to multiple imputation for dealing with missing data. There are plans to create multiple imputations for the years 2018 and beyond as. Software using a propensity score classifier with the approximate bayesian bootstrap produces badly biased estimates of regression coefficients when data on predictor variables are missing at random or missing completely at random. Accounting for missing data in statistical analyses. The following is the procedure for conducting the multiple imputation for missing data that was created by.